ea0041gp193 | Thyroid - Basic | ECE2016
Kizilirmak Cise
, Qatato Maria
, Weber Jonas
, Rehders Maren
, Fuhrer Dagmar
, Brix Klaudia
BackgroundThyroid hormone transporting proteins Mct8 and Mct10 have been detected at the plasma membrane of thyroid epithelial cells, whereas Lat2 was found predominantly at vesicular membranes. In this study we look into the effects of inhibiting thyroid hormone transporters on their subcellular localisation to better understand their fate and trafficking pathways in thyrocytes. Thus, a pharmacological intervention study with specific inhibitors of thyr...